Biological ActivityAntagonist of 14.3.3 proteins (KD ≈80 nM). Competitively inhibits 14.3.3-ligand interactions without requiring phosphorylation. Blocks the ability of 14.3.3 to bind to target proteins such as Raf-1, Bad, ASK1 and exoenzyme S.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Isolation of high-affinity peptide antagonists of 14.3.3 proteins by phage display.
Wang et al.
14.3.3 proteins mediate an essential anti-apoptotic signal.
Masters and Fu
Survival-promoting functions of 14.3.3 proteins.
Masters et al.
No product specific FAQs exist for this product, however you mayView all Peptide FAQs
Reviews for R18
There are currently no reviews for this product. Be the first to review R18 and earn rewards!
Have you used R18?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image