rac-CCT 250863

Tocris Bioscience | Catalog # 4546

Potent Nek2 inhibitor
Tocris Bioscience

Key Product Details

Description

Potent Nek2 inhibitor
View all Nek2 Kinase Inhibitors »

Product Description

rac-CCT 250863 is a potent Nek2 inhibitor (IC50 = 73 nM). Exhibits selectivity for Nek2 over PLK1, MPS1, Cdk2 and Aurora A.

Product Specifications for rac-CCT 250863

Molecular Weight

490.54

Formula

C24H25F3N4O2S

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

4-[2-Amino-5-[4-[(dimethylamino)methyl]-2-thienyl]-3-pyridinyl]-2-[[(2Z)-4,4,4-trifluoro-1-methyl-2-buten-1-yl]oxy]benzamide

CAS Number

1364269-06-6

PubChem ID

57386035

InChI Key

LLEOOSLUHRQCHZ-SREVYHEPSA-N

SMILES

CN(C)CC1=CSC(C2=CN=C(N)C(C3=CC(OC(/C=C\C(F)(F)F)C)=C(C(N)=O)C=C3)=C2)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
1eq. HCl 49.05 100
DMSO 49.05 100

Preparing Stock Solutions for rac-CCT 250863

The following data is based on the product molecular weight 490.54.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.04 mL 10.19 mL 20.39 mL
5 mM 0.41 mL 2.04 mL 4.08 mL
10 mM 0.20 mL 1.02 mL 2.04 mL
50 mM 0.04 mL 0.20 mL 0.41 mL

Calculators

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

x
=
x

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product.

Product Documents for rac-CCT 250863

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for rac-CCT 250863

For research use only

Customer Reviews for rac-CCT 250863

There are currently no reviews for this product. Be the first to review rac-CCT 250863 and earn rewards!

Have you used rac-CCT 250863?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card