Recombinant Human RAR alpha/NR1B1 His Protein

Novus Biologicals | Catalog # NBC1-22578

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
View all RAR alpha/NR1B1 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a His-tag corresponding to amino acids 68 - 173 of RARA.

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSEEIVPSPP SPPPLPRIYK PCFVCQDKSS GYHYGVSACE GCKGFFRRSI QKNMVYTCHR DKNCIINKVT RNRCQYCRLQ KCFEVGMSKE SVRNDRNKKK KEVPKPE

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

14 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human RAR alpha/NR1B1 His Protein

SDS-PAGE: Recombinant Human RAR alpha/NR1B1 His Protein [NBC1-22578]

SDS-PAGE: Recombinant Human RAR alpha/NR1B1 His Protein [NBC1-22578]

SDS-Page: Retinoic Acid Receptor alpha Protein [NBC1-22578] - RARa, 14 kDa (127 aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

Formulation, Preparation, and Storage

NBC1-22578
Formulation PBS (pH 7.4), 10% glycerol, 1mM DTT, 0.1M NaCl
Preservative No Preservative
Concentration 1.0 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RAR alpha/NR1B1

Retinoic acid receptors (RAR) belong to the large family of ligand responsive gene regulatory proteins that includes receptors for steroid and thyroid hormones. These proteins contain two highly conserved domains that are involved in determining their DNA and ligand-binding activities. Three isotypes of RARs, alpha, beta, and gamma, are encoded by distinct genetic loci and possess distinct transcriptional properties. Typically, RAR-alpha represses target gene transcription in the absence of hormone, whereas RAR-beta and gamma fail to repress under these conditions. Recombinant human RARalpha, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Long Name

Retinoic Acid Receptor, alpha

Alternate Names

NR1B1, RARA

Gene Symbol

RARA

Additional RAR alpha/NR1B1 Products

Product Documents for Recombinant Human RAR alpha/NR1B1 His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human RAR alpha/NR1B1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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