RCE1 Recombinant Protein Antigen

Novus Biologicals | Catalog # NBP3-17425PEP

Novus Biologicals
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Key Product Details

Source

E. coli

Applications

Antibody Competition
View all RCE1 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human RCE1

Source: E. coli

Amino Acid Sequence: LTDPKLYGSLPLCVLLERAGDSEAPLCS

Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

Purity

>80% by SDS-PAGE and Coomassie blue staining

Predicted Molecular Mass

21 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Applications

Antibody Competition (10-100 molar excess)

Application Notes

This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP3-17425.

It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

Protein / Peptide Type

Recombinant Protein Antigen

Formulation, Preparation, and Storage

NBP3-17425PEP
Formulation PBS and 1M Urea, pH 7.4.
Preservative No Preservative
Concentration Please see the vial label for concentration. If unlisted please contact technical services.
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: RCE1

RCE1, also known as CAAX prenyl protease 2, is a 36 kDa 329 amino acid protein found in the endoplasmic reticulum membrane. The primary function of RCE1 is to encode a protein that plays a signifcant role in the processing and maintenance of CAAX-type proteins. Research is being conducted on RCE1 in relation tofollicular mucinosis, mandibuloacral dysplasia, phaeohyphomycosis, Legionnaires' disease, impetigo, cardiomyopathy. RCE1 is linked to the G-protein signaling Rap1A regulation pathway where it interacts with ICMT, UBC, EIF3F and ZMPSTE24.

Alternate Names

CAAX prenyl protease 2, EC 3.4.22.-, FACE-2, FACE2RCE1 homolog, prenyl protein protease (S. cerevisiae), farnesylated protein-converting enzyme 2, Farnesylated proteins-converting enzyme 2, hRCE1, Prenyl protein-specific endoprotease 2, RCE1 (S. Cerevisiae) homolog, prenyl protein protease, RCE1 homolog, RCE1 homolog, prenyl protein peptidase (S. cerevisiae), RCE1 homolog, prenyl protein protease, RCE1A, RCE1B

Gene Symbol

RCE1

Additional RCE1 Products

Product Documents for RCE1 Recombinant Protein Antigen

Certificate of Analysis

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Product Specific Notices for RCE1 Recombinant Protein Antigen

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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