Repaglinide

Key Product Details

Product Description

Repaglinide is a K_ir6 (K_ATP) channel blocker that binds with high affinity for SUR1 when co-expressed with K_ir6.2 (K_d = 0.42 nM). Antidiabetic glucose regulator with hypoglycaemic effect in vivo.

Product Specifications for Repaglinide

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Repaglinide

The following data is based on the product molecular weight 452.59.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.21 mL	11.05 mL	22.10 mL
5 mM	0.44 mL	2.21 mL	4.42 mL
10 mM	0.22 mL	1.10 mL	2.21 mL
50 mM	0.04 mL	0.22 mL	0.44 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

• Hansen Kir6.2-dependent high-affinity repagl. binding to β-cell K_ATP channels. Br.J.Pharmacol. 2005 PMID: 15678092
• Mark and Grell Hypoglycaemic effects of the novel antidiabetic agent repagl. in rats and dogs. Br.J.Pharmacol. 1997 PMID: 9283692

Product Documents for Repaglinide