Binds the vesicular monoamine transporter (VMAT2) and inhibits transport of biogenic amines into adrenal chromaffin granules and synaptic vesicles. Causes depletion of biogenic amine stores. Antihypertensive and antipsychotic.
Soluble to 10 mM in DMSO
Store at RT
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Reserpine binding to a vesicular amine transporter expressed in chinese hamster ovary fibroblasts.
Schuldiner et al.
Effect of reserpine on behavioural responses to agonists at 5-HT1A, 5-HT1B, 5-HT2A, and 5-HT2C receptor subtypes.
Heslop and Curzon
Inhibitory effect of reserpine on dopamine transporter function.
Metzger et al.
The citations listed below are publications that use Tocris products. Selected citations for Reserpine include:
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