Resiquimod

Catalog # Availability Size / Price Qty
4536/10
4536/50
Resiquimod | CAS No. 144875-48-9 | Toll-like Receptor Agonists
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Description: Toll-like receptor 7 (TLR7) agonist
Alternative Names: R 848

Chemical Name: 1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol

Purity: ≥98%

Product Details
Supplemental Products
Reviews (1)

Biological Activity

Toll-like receptor 7 (TLR7) agonist. Induces upregulation of IL-6, IL-12, IFN-γ and iNOS expression in mouse bone marrow-derived macrophages (BMMs). Inhibits RANKL-induced osteoclast differentiation in mouse BMMs and human peripheral blood monocytes. Also promotes the differentiation of MDSCs into macrophages and dendritic cells. Proinflammatory and antiviral.

Technical Data

M.Wt:
314.38
Formula:
C17H22N4O2
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
144875-48-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Good, stores well
By Scott Scarneo on 02/06/2019
Application: Species: Mouse

Worked well for macrophages and got the desired result by TNF production.


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