Catalog Number: 5761
Alternate Names: RSL1
Chemical Name: 2-Ethyl-3-methoxybenzoic acid 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide
Biological Activity
Gene switch ligand. Transcription inducer for use in induceable gene expression systems. Does not cause significant changes in endogenous gene expression in HEK cells.
Technical Data
  • M.Wt:
    382.5
  • Formula:
    C23H30N2O3
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    162326-49-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Effect of ecdysone receptor gene switch ligands on endogenous gene expression in 293 cells.
    Panguluri et al.
    FEBS Journal, 2007;274:5669
  2. Semi-synthetic ecdysteroids as gene-switch actuators: synthesis, structure-activity relationships, and prospective ADME properties.
    Lapenna et al.
    ChemMedChem, 2009;4:55
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