RGD peptide

Catalog # Availability Size / Price Qty
7723/10
RGD peptide
1 Image
Description: Minimal recognition sequence for integrin binding; potent integrin inhibitor

Purity: ≥95%

Product Details
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Biological Activity

RGD peptide is a potent integrin inhibitor (IC50 values are 89, 335 and 440 nM for αvβ3, α5β1 and αvβ5, respectively). RGD is the minimal recognition sequence for integrin binding found in many extracellular matrix (ECM) and serum proteins. RGD peptide is used for directing association of various cell types with diverse biomaterials.  The functionality of RGD peptide is usually maintained throughout the processing and sterilization steps required for biomaterials synthesis. RGD peptide can be incorporated into hyaluronic acid hydrogel for human mesenchymal stem cells (hMSCs) delivery. RGD peptide significantly increases hMSC spreading and protein secretion under standard or ischemic culture conditions. RGD peptide can also be incorporated into alginate bioink for 3D bioprinting of MSCs onto cartilage templates for bone organogenesis.

Technical Data

M.Wt:
346.34
Formula:
C12H22N6O6
Sequence:
RGD
Solubility:
Soluble to 10 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
99896-85-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Reconstitution Calculator

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