Riluzole hydrochloride

  ( 9 citations )    
Product Datasheet
Catalog Number:0768
Chemical Name:2-Amino-6-trifluoromethoxybenzothiazole hydrochloride
Product Details
Citations (9)
Reviews
Biological Activity
Psychotropic agent with anticonvulsant, hypnotic, anxiolytic, anti-ischemic and anesthetic properties. Inhibits glutamate release from presynaptic terminals and increases Na+-dependent glutamate uptake in rat cortical synaptosomes. Blocks voltage-dependent Na+ channels and inhibits GABA uptake by striatal synaptosomes; neuroprotective.
Technical Data
  • M.Wt:
    270.66
  • Formula:
    C8H5F3N2OS.HCl
  • Solubility:
    Soluble to 100 mM in DMSO and to 10 mM in water with gentle warming
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    850608-87-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
COA view current batch
or select another batch:
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Riluzole hydrochloride include:

9 Citations: Showing 1 - 9
Filter your results:

  1. Targeting Glutamatergic Signaling and the PI3 Kinase Pathway to Halt Melanoma Progression.
    Authors: Rosenberg Et al.
    Front Neural Circuits  2015;8:42614
  2. Generation and expansion of highly pure motor neuron progenitors from human pluripotent stem cells.
    Authors: Du Et al.
    Nat Commun  2015;6:6626
  3. Generation and expansion of highly pure motor neuron progenitors from human pluripotent stem cells.
    Authors: Du Et al.
    Nat.Commun.  2015;6:6626
  4. Glutamate secretion and metabotropic glutamate receptor 1 expression during Kaposi's sarcoma-associated herpesvirus infection promotes cell proliferation.
    Authors: Veettil Et al.
    PLoS Pathog  2014;10:e1004389
  5. β-Noradrenergic receptor activation specifically modulates the generation of sighs in vivo and in vitro.
    Authors: Viemari Et al.
    Neurochem Int  2013;7:179
  6. Riluzole elevates GLT-1 activity and levels in striatal astrocytes.
    Authors: Carbone Et al.
    BMC Neurosci  2012;60:42613
  7. Riluzole neuroprotection in a Parkinson's disease model involves suppression of reactive astrocytosis but not GLT-1 regulation.
    Authors: Carbone Et al.
    Cells  2012;13:38
  8. Glycinergic pacemaker neurons in preBötzinger complex of neonatal mouse.
    Authors: Morgado-Valle Et al.
    J Neurosci  2010;30:3634
  9. The glutamate release inhibitor Riluzole decreases migration, invasion, and proliferation of melanoma cells.
    Authors: Le Et al.
    J Invest Dermatol  2010;130:2240

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Have you used Riluzole hydrochloride?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Contact Us to Order
reload

Feedback

Customer Information
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee