Rimcazole dihydrochloride

  ( 1 citations )    
Product Datasheet
Catalog Number:1497
Alternate Names:BW 234U
Chemical Name:9-[3-(cis-3,5-Dimethyl-1-piperazinyl)propyl]-9H-carbazole dihydrochloride
Product Details
Citations (1)
Reviews
Biological Activity
Antagonist at σ receptors (IC50 values are 1480 and 386 nM at σ1 and σ2 receptors respectively). Also binds to the dopamine transporter (IC50 = 57.6 nM) and inhibits dopamine uptake. Reduces the stimulatory effects of cocaine in vivo.
Technical Data
  • M.Wt:
    394.39
  • Formula:
    C21H27N3.2HCl
  • Solubility:
    Soluble to 10 mM in water
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    75859-03-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Rimcazole dihydrochloride include:

1 Citations: Showing 1 - 1

  1. σ1 receptor ligands control a switch between passive and active threat responses.
    Authors: Rennekamp Et al.
    Nat Chem Biol  2016;12:552

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