Catalog Number: 3393
Biological Activity
Reversed amino acid sequence control peptide for TFLLR-NH2, a PAR1 selective agonist that significantly increases nociceptive threshold.

Active Analog also available.

Technical Data
  • M.Wt:
    647.82
  • Formula:
    C31H53N9O6
  • Sequence:
    RLLFT

    (Modifications: Thr-5 = C-terminal amide)

  • Solubility:
    Soluble to 2 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    447408-68-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Proteinase-activated receptor-1 agonists attenuate nociception in response to noxious stimuli.
    Asfaha et al.
    Br.J.Pharmacol., 2002;135:1101
  2. Thrombin inhibits NMDA-mediated nociceptive activity in the mouse: possible mediation by endothelin.
    Fang et al.
    J.Physiol., 2003;549:903
  3. Activation of proteinase-activated receptor-1 inhibits neurally evoked chloride secretion in the mouse colon in vitro.
    Buresi et al.
    Am.J.Physiol.Gastrointest.Liver Physiol., 2004;288:G337
Citations:

The citations listed below are publications that use Tocris products. Selected citations for RLLFT-NH2 include:

1 Citations: Showing 1 - 1

  1. Thrombin activity associated with neuronal damage during acute focal ischemia.
    Authors: Chen Et al.
    J Neurosci 2012;32:7622
Tocris Peptides
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TFLLR-NH2

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