Biological ActivityReversed amino acid sequence control peptide for TFLLR-NH2, a PAR1 selective agonist that significantly increases nociceptive threshold.
Active Analog also available.
(Modifications: Thr-5 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Proteinase-activated receptor-1 agonists attenuate nociception in response to noxious stimuli.
Asfaha et al.
Thrombin inhibits NMDA-mediated nociceptive activity in the mouse: possible mediation by endothelin.
Fang et al.
Activation of proteinase-activated receptor-1 inhibits neurally evoked chloride secretion in the mouse colon in vitro.
Buresi et al.
Am.J.Physiol.Gastrointest.Liver Physiol., 2004;288:G337
Citation for RLLFT-NH2
The citations listed below are publications that use Tocris products. Selected citations for RLLFT-NH2 include:
1 Citation: Showing 1 - 1
Thrombin activity associated with neuronal damage during acute focal ischemia.
Authors: Chen Et al.
J Neurosci 2012;32:7622
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VersaClone cDNA Plasmids
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