TFLLR-NH2
Tocris Bioscience | Catalog # 1464
Key Product Details
Description
Product Description
TFLLR-NH2 is a peptide derived from the protease-activated receptor-1 (PAR1) that acts as a PAR1 selective agonist (EC50 = 1.9 μM). Stimulates PAR1-mediated plasma extravasation in vivo.
Control Peptide also available.
Product Specifications for TFLLR-NH2
Molecular Weight
Formula
Storage
Purity
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 36 publications citing the usage of this product.
- Hollenberg Proteinase-activated receptors: structural requirements for activity, receptor cross-reactivity, and receptor selectivity of receptor-activating peptides. Can.J.Physiol.Pharmacol. 1997 PMID: 9315351
- Kawabata Characterization of the protease-activated receptor-1-mediated contraction and relaxation in the rat duodenal smooth muscle. Life Sci. 2000 PMID: 11065174
- de Garavilla Agonists of proteinase-activated receptor 1 induce plasma extravasation by a neurogenic mechanism. Br.J.Pharmacol. 2001 PMID: 11487506
Product Documents for TFLLR-NH2
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for TFLLR-NH2
For research use only
Citations for TFLLR-NH2
Customer Reviews for TFLLR-NH2 (2)
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Species: HumanAssay Type: In VitroCell Line/Tissue: HASM cellVerified Customer | Posted 04/06/2021Effect of TFLLR-NH2 on PLCbeta activity in HASMCs
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Assay Type: Ex VivoVerified Customer | Posted 12/16/20185uM TFLLR-NH2 was treated on platelets and the TGFb1 release was measured by ELISA.
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