Recombinant Human RND3 His Protein

Novus Biologicals | Catalog # NBP1-45303

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
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Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-241 of Human RND3

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MKERRASQKL SSKSIMDPNQ NVKCKIVVVG DSQCGKTALL HVFAKDCFPE NYVPTVFENY TASFEIDTQR IELSLWDTSG SPYYDNVRPL SYPDSDAVLI CFDISRPETL DSVLKKWKGE IQEFCPNTKM LLVGCKSDLR TDVSTLVELS NHRQTPVSYD QGANMAKQIG AATYIECSAL QSENSVRDIF HVATLACVNK TNKNVKRNKS QRATKRISHM PSRPELSAVA TDLRKDKAKS C

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

29.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human RND3 His Protein

Western Blot: Recombinant Human RND3 His Protein [NBP1-45303]

Western Blot: Recombinant Human RND3 His Protein [NBP1-45303]

Western Blot: RND3 Protein [NBP1-45303] - 15% SDS-PAGE (3ug)

Formulation, Preparation, and Storage

NBP1-45303
Formulation 20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT, 40% glycerol, 1 mM EDTA, 0.1 M NaCl
Preservative No Preservative
Concentration 0.5 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RND3

Rho-related GTP-binding protein RhoE, also known as RND3, is a small GTPase of the Ras superfamily that regulate the organization of the actin cytoskeleton in response to extracellular growth factors. RND3 activity leads to a decrease in stress fibers and increased cell migration, at least in part through regulation of the Rho-dependent kinase ROCK1. Also, RND3 has been implicated in inhibition of DNA-damage induced apoptosis and cell cycle arrest. Recombinant human RND3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Long Name

Rho family GTPase 3

Alternate Names

ARHE, MemB, Rho8

Gene Symbol

RND3

Additional RND3 Products

Product Documents for Recombinant Human RND3 His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human RND3 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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