Ro 0437626

Catalog # Availability Size / Price Qty
2188/1
2188/10
Ro 0437626 | CAS No. 134362-79-1 | P2X Receptor Antagonists
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Description: Selective P2X1 antagonist

Chemical Name: N-[(1R)-2-[[(1S,2R,3S)-1-(Cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]amino]-2-oxo-1-(4-thiazolylmethyl)ethyl]-1H-benzimidazole-2-carboxamide

Purity: ≥98%

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Biological Activity

Selective P2X1 purinergic receptor antagonist (IC50 = 3 μM) that displays > 30-fold selectivity over P2X2, P2X3 and P2X2/3 receptors (IC50 > 100 μM).

Technical Data

M.Wt:
525.66
Formula:
C27H35N5O4S
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
134362-79-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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