Ro 10-5824 dihydrochloride

Catalog # Availability Size / Price Qty
2329/10
2329/50
Ro 10-5824 dihydrochloride | CAS No. 189744-94-3 | Dopamine D4 Receptor Agonists
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Description: Selective D4 partial agonist

Chemical Name: 5-[(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)methyl]-2-methyl-4-pyrimidinamine dihydrochloride

Purity: ≥99%

Product Details
Citations (1)
Reviews

Biological Activity

Selective dopamine D4 receptor partial agonist (EC50 = 205 nM) that binds with high affinity (Ki = 5.2 nM). Displays 250-fold selectivity over D3 receptors and > 1000-fold selectivity over D2, D1 and D5 receptors.

Technical Data

M.Wt:
353.29
Formula:
C17H20N4.2HCl
Solubility:
Soluble to 100 mM in water and to 75 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
189744-94-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for Ro 10-5824 dihydrochloride

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