Ro 10-5824 dihydrochloride

Key Product Details

Product Description

Ro 10-5824 dihydrochloride is a selective dopamine D₄ receptor partial agonist (EC₅₀ = 205 nM) that binds with high affinity (K_i = 5.2 nM). Displays 250-fold selectivity over D₃ receptors and > 1000-fold selectivity over D₂, D₁ and D₅ receptors.

Product Specifications for Ro 10-5824 dihydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Ro 10-5824 dihydrochloride

The following data is based on the product molecular weight 353.29.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.83 mL	14.15 mL	28.31 mL
5 mM	0.57 mL	2.83 mL	5.66 mL
10 mM	0.28 mL	1.42 mL	2.83 mL
50 mM	0.06 mL	0.28 mL	0.57 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Powell RO-10-5824 is a selective DA D4 receptor agonist that increases novel object exploration in C57 mice. Neuropharmacology 2003 PMID: 12646284

Product Documents for Ro 10-5824 dihydrochloride