RO 5263397 hydrochloride

Catalog # Availability Size / Price Qty
6833/25
6833/5
RO 5263397 hydrochloride | Trace Amine 1 (TA1) Receptor Agonists
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Description: Potent TA1 receptor agonist

Chemical Name: (4S)-4-(3-Fluoro-2-methylphenyl)-4,5-dihydro-2-oxazolamine hydrochloride

Purity: ≥98%

Product Details
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Biological Activity

Potent trace amine 1 (TA1) receptor agonist (EC50 values are 0.12, 35 and 17-85 nM for mouse, rat and human receptors, respectively). Increases wakefulness and reduces REM and NREM sleep duration in wild type mice. Inhibits spontaneous locomotor activity in dopamine transport (DAT) knockout mice.

Technical Data

M.Wt:
230.67
Formula:
C10H11FN2O.HCl
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in water
Purity:
≥98%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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