Potent, selective 5-HT2
receptor agonist; shows selectivity for the 5-HT2C
values are 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C
receptors respectively). Centrally active following oral or systemic administration in vivo
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: novel 5-HT2A/5-HT2C receptor agonists with pro-cognitive
Jensen et al.
Neuroendocrine evidence that (S)-2-(chloro-5-fluoro-indol-l-yl)-1-methylethylamine fumarate (Ro 60-0175) is not a selective 5-hydroxytryptamine2C receptor agonist.
Damjanoska et al.
Effects of Ro 60 0175, a 5-HT2C receptor agonist, in three animal models of anxiety.
Kennett et al.
5-HT2C receptor agonists: pharmacological characteristics and therapeutic potential.
Martin et al.
The citations listed below are publications that use Tocris products. Selected citations for Ro 60-0175 fumarate include:
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