Catalog Number: 0728
Chemical Name: 3-(Piperidin-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride
Biological Activity
A high affinity, selective competitive antagonist at 5-HT4 receptors.
Technical Data
  • M.Wt:
    363.28
  • Formula:
    C16H23ClN2O3.HCl
  • Solubility:
    Soluble to 100 mM in water
  • Storage:
    Store at RT
  • CAS No:
    149719-06-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold with the permission of Roche Bioscience
Background References
  1. RS 23597-190: a potent and selective 5-HT4 receptor antagonist.
    Eglen et al.
    Br.J.Pharmacol., 1993;110:119
  2. Central 5-HT4 receptors.
    Eglen et al.
    TiPS, 1995;16:391
Citations:

The citations listed below are publications that use Tocris products. Selected citations for RS 23597-190 hydrochloride include:

3 Citations: Showing 1 - 3
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  1. Neuregulin-1 enhances depolarization-induced GABA release.
    Authors: Woo Et al.
    Neuron 2007;54:599
  2. 5-Hydroxytryptamine induces a protein kinase A/mitogen-activated protein kinase-mediated and macromolecular synthesis-dependent late phase of long-term potentiation in the amygdala.
    Authors: Huang and Kandel
    J Pharmacol Exp Ther 2007;27:3111
  3. Direct GABAergic and glycinergic inhibition of the substantia gelatinosa from the rostral ventromedial medulla revealed by in vivo patch-clamp analysis in rats.
    Authors: Kato Et al.
    J Neurosci 2006;26:1787

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