RS 246204

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8853/50
8853/10

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RS 246204 | CAS No. 878451-87-7 | Compounds for Stem Cell Proliferation and Renewal
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Description: R-Spondin-1 substitute used to initiate small intestinal organoids

Chemical Name: 3,7-Dihydro-3,7-dimethyl-8-(2-quinolinylthio)-1H-purine-2,6-dione

Purity: ≥98%

Product Details
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Biological Activity

RS 246204 is a R-Spondin-1 substitute. Able to initiate formation and growth of mouse intestinal organoids in media without R-Spondin-1 protein. In vivo, RS 24620 has regenerative effect in damaged intestinal epithelium mouse model.

Technical Data

M.Wt:
339.37
Formula:
C16H13N5O2S
Solubility:
Soluble to 5 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
878451-87-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Effects of a small molecule R-spondin-1 substitute RS-246204 on a mouse intestinal organoid culture.
    Nam MO, Hahn S, Jee JH, Hwang TS.
    Oncotarget.

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