RS 25344 hydrochloride

Catalog # Availability Size / Price Qty
3315/10
3315/50
RS 25344 hydrochloride | CAS No. 152815-28-6 | Phosphodiesterase Inhibitors
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Description: Potent PDE4 inhibitor

Chemical Name: 1-(3-Nitrophenyl)-3-(4-pyridinylmethyl)-pyrido[2,3-d]pyrimidine-2,3-(1H,3H)-dione hydrochloride

Purity: ≥98%

Product Details
Citations (1)
Reviews

Biological Activity

Potent and selective phosphodiesterase (PDE) 4 inhibitor (IC50 values are 0.28, > 100, 160 and 330 nM at PDE4, PDE1, PDE2 and PDE3 respectively). Inhibits eosinophil chemotaxis and increases progressive motility of spermatozoa in vitro.

Technical Data

M.Wt:
411.8
Formula:
C19H13N5O4.HCl
Solubility:
Soluble to 50 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
152815-28-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for RS 25344 hydrochloride

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