RS 56812 hydrochloride

Key Product Details

Product Description

RS 56812 hydrochloride is a highly potent and selective 5-HT₃ partial agonist, with a pK_i at 5-HT₃ receptors in rat brain of 9.6, and greater than 1000-fold selectivity over a wide range of other neurotransmitter receptors.

Licensing Information

Sold with the permission of Roche Bioscience

Product Specifications for RS 56812 hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for RS 56812 hydrochloride

The following data is based on the product molecular weight 347.84.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.87 mL	14.37 mL	28.75 mL
5 mM	0.57 mL	2.87 mL	5.75 mL
10 mM	0.29 mL	1.44 mL	2.87 mL
50 mM	0.06 mL	0.29 mL	0.57 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Clark N-(Quinuclidin-3-yl)-2-(1-methyl-1H-indol-3-yl)-2-oxoacetamide: a high affinity 5-HT₃ receptor partial agonist. Bioorg.Med.Chem.Lett.

Product Documents for RS 56812 hydrochloride