(RS)-APICA

  ( 2 citations )    
Product Datasheet
Catalog Number:1073
Chemical Name:(RS)-1-Amino-5-phosphonoindan-1-carboxylic acid
Product Details
Citations (2)
Supplemental Products
Reviews
Biological Activity
Rigidified analog of MPPG (Cat. No. 0853); selective group II metabotropic glutamate receptor antagonist (IC50 = 30 μM) with no significant effect on group I and III mGlu receptors at concentrations up to 1 mM. Increases extracellular glutamate concentrations and possesses unusual inverse agonist-like action.
Technical Data
  • M.Wt:
    257.18
  • Formula:
    C10H12NO5P
  • Solubility:
    Soluble to 100 mM in 1.1eq. NaOH
  • Storage:
    Desiccate at +4°C
  • CAS No:
    170847-18-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
COA view current batch
or select another batch:
Citations:

The citations listed below are publications that use Tocris products. Selected citations for (RS)-APICA include:

2 Citations: Showing 1 - 2
Filter your results:

  1. HTS-compatible FRET-based conformational sensors clarify membrane receptor activation.
    Authors: Scholler
    Nat Chem Biol  2017;13(4):372
  2. Activation of group III metabotropic glutamate receptors attenuates rotenone toxicity on dopaminergic neurons through a microtubule-dependent mechanism.
    Authors: Jiang Et al.
    J Neurosci  2006;26:4318

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Have you used (RS)-APICA?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Contact Us to Order
reload

Feedback

Customer Information
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee