Chemical Name:(RS)-1-Amino-5-phosphonoindan-1-carboxylic acid
Biological Activity Rigidified analog of MPPG (Cat. No. 0853); selective group II metabotropic glutamate receptor antagonist (IC50 = 30 μM) with no significant effect on group I and III mGlu receptors at concentrations up to 1 mM. Increases extracellular glutamate concentrations and possesses unusual inverse agonist-like action.
Soluble to 100 mM in 1.1eq. NaOH
Desiccate at +4°C
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