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Catalog Number:1073
Chemical Name:(RS)-1-Amino-5-phosphonoindan-1-carboxylic acid
Product Details
Citations (2)
Supplemental Products
Reviews
Biological Activity
Rigidified analog of MPPG (Cat. No. 0853); selective group II metabotropic glutamate receptor antagonist (IC50 = 30 μM) with no significant effect on group I and III mGlu receptors at concentrations up to 1 mM. Increases extracellular glutamate concentrations and possesses unusual inverse agonist-like action.
Rigidified analog of MPPG (Cat. No. 0853); selective group II metabotropic glutamate receptor antagonist (IC50 = 30 μM) with no significant effect on group I and III mGlu receptors at concentrations up to 1 mM. Increases extracellular glutamate concentrations and possesses unusual inverse agonist-like action.
Technical Data
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M.Wt:257.18
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Formula:C10H12NO5P
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Solubility:Soluble to 100 mM in 1.1eq. NaOH
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Storage:Desiccate at +4°C
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CAS No:170847-18-4
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
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Citations:
The citations listed below are publications that use Tocris products. Selected citations for (RS)-APICA include:
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