Catalog Number: 0912
Chemical Name: 5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole hemisuccinate
Biological Activity
Potent 5-HT1A/1B and moderate 5-HT2C agonist that may also release 5-HT. Centrally active following systemic administration.
Technical Data
  • M.Wt:
    287.34
  • Formula:
    C14H16N2O.½C4H6O4
  • Solubility:
    Soluble to 50 mM in DMSO and to 30 mM in water
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    66611-27-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Human S31 serotonin receptor clone encodes a 5-hydroxytryptamine1E-like serotonin receptor.
    Gudermann et al.
    Mol.Pharmacol., 1993;43:412
  2. Effect of 5-HT1B receptor ligands on self-administration of ethanol in an operant procedure in rats.
    Tomkins and O'Neill
    Pharmacol.Biochem.Behav., 2000;66:129
  3. Synthesis of 3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles and study of their serotonergic and antidopaminergic properties.
    Guillaume et al.
    Eur.J.Med.Chem., 1987;22:33
Citations:

The citations listed below are publications that use Tocris products. Selected citations for RU 24969 hemisuccinate include:

1 Citations: Showing 1 - 1

  1. Effects of Oxytocin on Serotonin 1B Agonist-induced Autism-like Behavior in Mice
    Authors: Lawson Et al.
    Behavioural Brain Research 2016;314:52

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