Catalog Number: 3828
Alternate Names: CGP 33101
Chemical Name: 1-[(2,6-Difluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamide
Biological Activity
Board spectrum anticonvulsant. Prolongs the inactivation of sodium channels and limits the frequency of action potential firing in cultured and acutely isolated neurons. Displays anticonvulsive activity in a range of animal seizure models.
Technical Data
  • M.Wt:
    238.19
  • Formula:
    C10H8F2N4O
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Desiccate at RT
  • CAS No:
    106308-44-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Diverse mechanisms of antiepileptic drugs in the development pipeline.
    Rogawski et al.
    Epilepsy Res., 2006;69:273
  2. Rufinamide.
    Arroyo
    Neurotherapeutics, 2007;4:155
  3. The anticonvulsant profile of rufinamide (CGP 33101) in rodent seizure models.
    White et al.
    Epilepsia, 2008;49:1213

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