Rufinamide

Key Product Details

Product Description

Rufinamide is a board spectrum anticonvulsant. Prolongs the inactivation of sodium channels and limits the frequency of action potential firing in cultured and acutely isolated neurons. Displays anticonvulsive activity in a range of animal seizure models.

Product Specifications for Rufinamide

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Rufinamide

The following data is based on the product molecular weight 238.19.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.20 mL	20.99 mL	41.98 mL
5 mM	0.84 mL	4.20 mL	8.40 mL
10 mM	0.42 mL	2.10 mL	4.20 mL
50 mM	0.08 mL	0.42 mL	0.84 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

• Arroyo Rufinamide. Neurotherapeutics 2007 PMID: 17199032
• White The anticonvulsant profile of rufin. (CGP 33101) in rodent seizure models. Epilepsia 2008 PMID: 18325020
• Rogawski Diverse mechanisms of antiepileptic drugs in the development pipeline. Epilepsy Res. 2006 PMID: 16621450

Product Documents for Rufinamide