Chemical Name: 1-[(2,6-Difluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamide
Biological ActivityRufinamide is a board spectrum anticonvulsant. Prolongs the inactivation of sodium channels and limits the frequency of action potential firing in cultured and acutely isolated neurons. Displays anticonvulsive activity in a range of animal seizure models.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Diverse mechanisms of antiepileptic drugs in the development pipeline.
Rogawski et al.
Epilepsy Res., 2006;69:273
The anticonvulsant profile of rufin. (CGP 33101) in rodent seizure models.
White et al.
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