Rupintrivir

Catalog # Availability Size / Price Qty
6414/5
Rupintrivir | CAS No. 223537-30-2 | 3C and 3CL Protease Inhibitors
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Description: Potent and selective irreversible human rhinovirus 3Cpro inhibitor

Chemical Name: Ethyl (2E,4S)-4-[[(2R,5S)-2-[(4-fluorophenyl)methyl]-6-methyl-5-[[(5-methyl-3-isoxazolyl)carbonyl]amino]-1,4-dioxoheptyl]amino]-5-[(3S)-2-oxo-3-pyrrolidinyl]-2-pentenoate

Purity: ≥98%

Product Details
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Biological Activity

Rupintrivir is a potent and selective irreversible human rhinovirus (HRV) 3C protease inhibitor (EC50 = 5 nM). Exhibits no significant inhibition against a variety of serine and cysteine proteases. Inhibits replication of a panel of 48 different HRV serotypes in H1-HeLA and MRC-5 cell protection assays.

Tocris products are for biomedical research use only. They are not intended for human or veterinary use.

Technical Data

M.Wt:
598.66
Formula:
C31H39FN4O7
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
223537-30-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.

Product Datasheets

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