11 results for "3C and 3CL Protease Inhibitors" in Products
3C and 3CL Protease Inhibitors
3C and 3C-like proteases are cysteine proteases identified in coronaviruses and picornaviruses, such as SARS-CoV, poliovirus and rhinovirus. The active form of these proteases is dimeric, with each monomer contributing a cysteine-histidine catalytic domain to the active site. The individual monomers are inactive without dimerization. 3C and 3CL proteases are essential to the life cycle of the virus, and are key to the proteolytic processing of polyproteins that are translated from viral RNA by ...
Proteasome and calpain inhibitor. Inhibits NF-κB activation
| Alternate Names: | Z-LLL-al,Z-Leu-Leu-Leu-CHO |
| Chemical Name: | N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-L-leucinamide |
| Purity: | ≥95% |
Non-selective PI 3-kinase inhibitor
| Chemical Name: | 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one |
| Purity: | ≥98% |
Reversibly stimulates SERCA Ca2+-ATPase; displays a range of other activities
| Alternate Names: | Tetraethylthiuram disulfide |
| Chemical Name: | Bis(diethylthiocarbamyoyl)disulfide |
Glutathione peroxidase mimic; peroxynitrite scavenger
| Chemical Name: | 2-Phenyl-1,2-benzisoselenazol-3(2H)-one |
| Purity: | ≥98% |
Coronavirus Mpro inhibitor
| Chemical Name: | tert-Butyl (1-((S)-1-(((S)-4-(benzylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-3-cyclopropyl-1-oxopropan-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)carbamate |
| Purity: | ≥97% |
Coronavirus Mpro inhibitor
| Chemical Name: | N-[(5-Methyl-3-isoxazolyl)carbonyl]-L-alanyl-L-valyl-N-[(1S,2E)-4-oxo-1-[[(3S)-2-oxo-3-pyrrolidinyl]methyl]-4-(phenylmethoxy)-2-buten-1-yl]-L-leucinamide |
| Purity: | ≥98% |
Potent non-covalent inhibitor of SARS-CoV-2 main protease
| Chemical Name: | 5-[5-[3-Chloro-5-[(2-chlorophenyl)methoxy]-4-fluorophenyl]-6-oxo[1(6H),3'-bipyridin]-3-yl]-1-methyl-2,4(1H,3H)-pyrimidinedione |
| Purity: | ≥95% |
Potent colony-stimulating factor 1 receptor (CSF-1R) tyroine kinase inhibitor
| Chemical Name: | 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide |
| Purity: | ≥98% |
Potent hepatitis C virus (HCV) NS3 protease inihibitor
| Chemical Name: | 1-[[N-tert-Butoxycarbonyl-L-tert-leucyl-trans-4-[(7-chloro-4-methoxyisoquinolin-1-yl)oxy]-L-prolyl]amino]-N-(cyclopropylsulfonyl)-(1R,2S)-2-vinylcyclopropane-1-carboxamide |
| Purity: | ≥98% |
Negative control for Mpro 13b-K (Cat. No. 7228)
| Chemical Name: | tert-Butyl (1-((R)-1-(((S)-4-(benzylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-3-cyclopropyl-1-oxopropan-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)carbamate |
| Purity: | ≥97% |
SARS-CoV-2 Mpro Degrader (PROTAC®)
| Chemical Name: | 3-((6-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)hexyl)oxy)benzyl ((2S,3R)-3-(tert-butoxy)-1-(((S)-3-cyclohexyl-1-oxo-1-(((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)amino)propan-2-yl)amino)-1-oxobutan-2-yl)carbamate |
