Selective inhibitor of LFA-1 (lymphocyte function-associated antigen-1) adhesion to soluble intercellular adhesion molecule (sICAM) (IC50
= 5 μ
M in HL60 cells).
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All Tocris products are intended for laboratory research use only.
Novel thiazole based heterocycles as inhibitors of LFA-1/ICAM-1 mediated cell adhesion.
Sanfilippo et al.