Chemical Name: N-(3-Hydroxypropyl)-5-methyl-1-[-4-[3-(trifluoromethyl)phenyl)]-2-thiazolyl]-1H-pyrazole-4-carboxamide
Biological ActivityRWJ 50271 is a selective inhibitor of LFA-1 (lymphocyte function-associated antigen-1) adhesion to soluble intercellular adhesion molecule (sICAM) (IC50 = 5 μM in HL60 cells).
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Novel thiazole based heterocycles as inhibitors of LFA-1/ICAM-1 mediated cell adhesion.
Sanfilippo et al.
Citation for RWJ 50271
The citations listed below are publications that use Tocris products. Selected citations for RWJ 50271 include:
1 Citation: Showing 1 - 1
Bone marrow-derived mesenchymal stem cells propagate immunosuppressive/anti-inflammatorymacrophages in cell-to-cell contact-independent and dependent manners under hypoxic culture.
Exp Cell Res 2017;358(2):441
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VersaClone cDNA Plasmids
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