Ryanodine Receptor 2 Antibody - BSA Free

Immunohistochemistry-Paraffin: Ryanodine Receptor 2 Antibody [NBP1-90091]

Immunohistochemistry-Paraffin: Ryanodine Receptor 2 Antibody [NBP1-90091] - Staining of human skeletal muscle shows no positivity in myocytes as expected.

Immunohistochemistry-Paraffin: Ryanodine Receptor 2 Antibody [NBP1-90091]

Immunohistochemistry-Paraffin: Ryanodine Receptor 2 Antibody [NBP1-90091] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neurons.

Immunohistochemistry: Ryanodine Receptor 2 Antibody - BSA Free [NBP1-90091] -

Validation of enriched RYR2 expression in Fezf2+ve IT-PNs by immunohistochemistry. Coronal sections from CTB647 injected Fezf2-Gfp mouse were labeled for Ryanodine receptor 2 (RYR2) expression and images captured in M1. (Ai) RYR2 expression in M1. (ii) Image shows co-expression of RYR2 (purple) with Fezf2+ve IT-PNs (green and red; arrowhead) and Fezf2−ve IT-PNs (red; asterisk). Dashed lines indicate layer 5 from which cells were selected for quantification. Scale bar is 100 μm. (B) Normalized percentage area of cell body labeled for RYR2 expression in Fezf2+ve and Fezf2−ve IT-PNs. There is a significant decrease of RYR2 protein expression in Fezf2−ve IT-PN cell bodies (p < 0.05, paired t-test, n = 3; +/- SEM). Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/30483051), licensed under a CC-BY license. Not internally tested by Novus Biologicals.