Catalog Number: 0329
Alternate Names: (S)-3C4HPG
Biological Activity
Mixed group I metabotropic glutamate receptor antagonist and group II mGlu agonist.

R-enantiomer also available.

Technical Data
  • M.Wt:
    211.17
  • Formula:
    C9H9NO5
  • Solubility:
    Soluble to 25 mM in water
  • Purity:
    >98%
  • Storage:
    Store at RT
  • CAS No:
    55136-48-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes.
    Sekiyama et al.
    Br. J. Pharmacol., 1996;117:1493
  2. Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor sub-types.
    Hayashi et al.
    J.Neurosci., 1994;14:3370
  3. Phenylglycine derivatives as antagonists of metabotropic glutamate receptors.
    Watkins and Collingridge
    TiPS, 1994;15:333
  4. Recent advances in the pharmacology of excitatory amino acids.
    Watkins et al.
    Excitatory Amino Acid Transmission. Eds. Hicks, Lo, 1987;:19-26

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