Biological ActivityMixed group I metabotropic glutamate receptor antagonist and group II mGlu agonist.
R-enantiomer also available.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor sub-types.
Hayashi et al.
Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes.
Sekiyama et al.
Recent advances in the pharmacology of excitatory amino acids.
Watkins et al.
Excitatory Amino Acid Transmission. Eds. Hicks, Lo, 1987;:19-26
Phenylglycine derivatives as antagonists of metabotropic glutamate receptors.
Watkins and Collingridge
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