(S)-3-Carboxy-4-hydroxyphenylglycine

Key Product Details

Product Description

(S)-3-Carboxy-4-hydroxyphenylglycine is a mixed group I metabotropic glutamate receptor antagonist and group II mGlu agonist.

R-enantiomer also available.

Product Specifications for (S)-3-Carboxy-4-hydroxyphenylglycine

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for (S)-3-Carboxy-4-hydroxyphenylglycine

The following data is based on the product molecular weight 211.17.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

4 3 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.25 mM	18.94 mL	94.71 mL	189.42 mL
1.25 mM	3.79 mL	18.94 mL	37.88 mL
2.5 mM	1.89 mL	9.47 mL	18.94 mL
12.5 mM	0.38 mL	1.89 mL	3.79 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Watkins Recent advances in the pharmacology of excitatory amino acids. Excitatory Amino Acid Transmission. Eds. Hicks, Lo
• Sekiyama Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br.J.Pharmacol. 1996 PMID: 8730745
• Watkins and Collingridge Phenylglycine derivatives as antagonists of metabotropic glutamate receptors. TiPS 1994 PMID: 7992387
• Hayashi Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor sub-types. J.Neurosci. 1994 PMID: 8182479

Product Documents for (S)-3-Carboxy-4-hydroxyphenylglycine