Catalog # Availability Size / Price Qty
Cat.No. 0329 - (S)-3-Carboxy-4-hydroxyphenylglycine | C9H9NO5 | CAS No. 55136-48-6
1 Image
Description: Group I antagonist/group II agonist
Alternative Names: (S)-3C4HPG

Purity: ≥98%

Product Details
Supplemental Products

Biological Activity

Mixed group I metabotropic glutamate receptor antagonist and group II mGlu agonist.

R-enantiomer also available.

Technical Data

Soluble to 25 mM in water
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Additional Information

Other Product-Specific Information:

Background References

  1. Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor sub-types.
    Hayashi et al.
    J.Neurosci., 1994;14:3370
  2. Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes.
    Sekiyama et al.
    Br.J.Pharmacol., 1996;117:1493
  3. Phenylglycine derivatives as antagonists of metabotropic glutamate receptors.
    Watkins and Collingridge
    TiPS, 1994;15:333
  4. Recent advances in the pharmacology of excitatory amino acids.
    Watkins et al.
    Excitatory Amino Acid Transmission. Eds. Hicks, Lo, 1987;:19-26

Product Datasheets

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