(S)-(-)-Carbidopa

Tocris Bioscience | Catalog # 0455

Aromatic L-amino acid decarboxylase inhibitor
Tocris Bioscience

Key Product Details

Description

Aromatic L-amino acid decarboxylase inhibitor
View all Decarboxylase Inhibitors »

Product Description

(S)-(-)-Carbidopa is a peripheral decarboxylase inhibitor, used in combination with levodopa for treatment of Parkinsonism.

Product Specifications for (S)-(-)-Carbidopa

Molecular Weight

226.23

Formula

C10H14N2O4

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(S)-α-Hydrazino-α-methyl-β-(3,4-dihydroxyphenyl)propionic acid

CAS Number

28860-95-9

PubChem ID

34359

InChI Key

TZFNLOMSOLWIDK-JTQLQIEISA-N

SMILES

OC1=C(O)C=CC(C[C@@](NN)(C)C(O)=O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 4.52 20

Preparing Stock Solutions for (S)-(-)-Carbidopa

The following data is based on the product molecular weight 226.23.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 22.10 mL 110.51 mL 221.01 mL
1 mM 4.42 mL 22.10 mL 44.20 mL
2 mM 2.21 mL 11.05 mL 22.10 mL
10 mM 0.44 mL 2.21 mL 4.42 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

  • Kopfhammer L-Dopa infusion experiments in combination with the L-dopa decarboxylase inhibitors benserazide and carb. - L-dopa metabolism and neuroendocrinological effects. Pharmacopsychiatry
  • Cheng Carbidopa inhibition of aromatic L-amino acid decarboxylase in rat brain capilliaries. FASEB J.

Product Documents for (S)-(-)-Carbidopa

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (S)-(-)-Carbidopa

For research use only

Citations for (S)-(-)-Carbidopa

Customer Reviews for (S)-(-)-Carbidopa (1)

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  • Carbidopa was used to understand it's effect on brain DDC conversion of levodopa/L-DOPA to dopamine
    Name: Provs Pantha
    Species: Human
    Verified Customer | Posted 08/16/2019
    Carbidopa acts as a peripheral DDC inhibitor, and carbidopa was used to understand it's effect on brain DDC conversion of levodopa/L-DOPA to dopamine.
    (S)-(-)-Carbidopa 0455

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