S26948

Catalog # Availability Size / Price Qty
3690/10
3690/50
S26948 | CAS No. 353280-43-0 | PPAR gamma Receptor Agonists
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Description: Selective PPARγ agonist; antidiabetic agent

Chemical Name: [[4-[2-(6-Benzoyl-2-oxo-3(2H)-benzothiazolyl)ethoxy]phenyl]methyl]-1,3-propanedioic acid dimethyl ester

Purity: ≥99%

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Biological Activity

Selective PPARγ agonist (EC50 = 8.83 nM). Drives normal adipocyte differentiation and exhibits a lipid-lowering effect; reduces atherosclerosis in E2-KI mice. Displays antidiabetic properties and improves hepatic insulin sensitivity in intralipid-infusion (IL) rats.

Technical Data

M.Wt:
519.57
Formula:
C28H25NO7S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
353280-43-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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