Chemical Name: 4-[[[(3,5-Dimethylphenyl)amino]carbonyl]amino]phenyl sulfamate
Biological Activity High affinity and selective CA IX and CA XII inhibitor (Ki values are 2, 7, 547 and 5600 nM for CA XII, IX, II and I, respectively). Inhibits migration and proliferation of breast cancer cells in vitro. Inhibits lung metastasis in mice bearing breast tumor xenografts, without affecting primary tumor.
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Store at +4°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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