SA 4503 dihydrochloride

Catalog # Availability Size / Price Qty
4951/10
4951/50
Cat.No. 4951 - SA 4503 dihydrochloride | C23H32N2O2.2HCl | CAS No. 165377-44-6
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Description: Selective σ1 receptor agonist

Chemical Name: 1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)-piperazine dihydrochloride

Purity: ≥98%

Product Details
Citations (1)
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Biological Activity

Selective σ1 receptor agonist (IC50 = 17.4 nM). Exhibits selectivity for σ1 over σ2 receptors. Inhibits angiotensin II-induced cardiomyocyte hypertrophy in vitro and attenuates myocardial hypertrophy in vivo. Enhances brain plasticity and sensorimotor function in a rat model of experimental stroke.

Technical Data

M.Wt:
441.43
Formula:
C23H32N2O2.2HCl
Solubility:
Soluble to 100 mM in water and to 20 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
165377-44-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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Citation for SA 4503 dihydrochloride

The citations listed below are publications that use Tocris products. Selected citations for SA 4503 dihydrochloride include:

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