Salmeterol xinafoate

Key Product Details

Product Description

Salmeterol xinafoate is a long-acting β₂ adrenergic receptor agonist. Inhibits the release of histamine, leukotrienes and prostaglandin D₂, and blocks GM-CSF production from human cultured mast cells. Exhibits efficacious bronchodilatory activity in patients with asthma or chronic obstructive pulmonary disease (COPD).

Product Specifications for Salmeterol xinafoate

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Salmeterol xinafoate

The following data is based on the product molecular weight 603.75.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.66 mL	8.28 mL	16.56 mL
5 mM	0.33 mL	1.66 mL	3.31 mL
10 mM	0.17 mL	0.83 mL	1.66 mL
50 mM	0.03 mL	0.17 mL	0.33 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 7 publications citing the usage of this product.

• Rennard Use of a long-acting inhaled beta2-adrenergic agonist, salme. xinafoate, in patients with chronic obstructive pulmonary disease. Am.J.Respir.Crit.Care Med. 2001 PMID: 11316640
• Roberts The long-acting beta2-agonist salme. xinafoate: effects on airway inflammation in asthma. Eur.Respir.J. 1999 PMID: 10515401
• Akabane Effects of salme. xinafoate and flutic. propionate on immunological activation of human cultured mast cells. Allergol.Int. 2006 PMID: 17130681

Product Documents for Salmeterol xinafoate