Cell-permeable, selective inhibitor of cellular phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α
). Protects cells from endoplasmic reticulum stress-induced apoptosis (EC50
~ 15 μ
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A selective inhibitor of eIF2α dephosphorylation protects cells from ER stress.
Boyce et al.
Structure-activity relationship studies of salubrinal lead to its active biotinylated derivative.
Long et al.
The citations listed below are publications that use Tocris products. Selected citations for Salubrinal include:
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