Catalog Number: 2134
Alternate Names: Divinorin A
Chemical Name: (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(Acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester
Biological Activity
Potent naturally occuring non-nitrogenous κ-opioid selective agonist that displays high affinity at both native (Ki = 4.3 nM) and cloned (Ki = 16 nM) κ-opioid receptors. Also exhibits allosteric modulation of μ-opioid receptor binding. Reported to be brain-penetrant and displays psychoactive properties.�.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 10 mM in ethanol
  • Purity:
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Salvinorin A: allosteric interactions at the μ-opioid receptor.
    Rothman et al.
    J.Pharmacol.Exp.Ther., 2007;320:801
  2. Salvinorin A: a potent naturally occuring nonnitrogenous κ opioid selective agonist.
    Roth et al.
    Proc.Natl.Acad.Sci.USA, 2002;99:11934

The citations listed below are publications that use Tocris products. Selected citations for Salvinorin A include:

Showing Results 1 - 1 of 1

  1. Naltrindole inhibits human multiple myeloma cell proliferation in vitro and in a murine xenograft model in vivo.
    Authors: Mundra Et al.
    J Pharmacol Exp Ther
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