Sarcosine

Key Product Details

Product Description

Sarcosine is an endogenous inhibitor of GlyT1 that displays antipsychotic activity. Potentiates the action of glycine on the NMDA glycine binding site.

Product Specifications for Sarcosine

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Sarcosine

The following data is based on the product molecular weight 89.09.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	11.22 mL	56.12 mL	112.25 mL
5 mM	2.24 mL	11.22 mL	22.45 mL
10 mM	1.12 mL	5.61 mL	11.22 mL
50 mM	0.22 mL	1.12 mL	2.24 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 8 publications citing the usage of this product.

• Singh and Singh Meta-analysis of the efficacy of adjunctive NMDA receptor modulators in chronic schizophrenia. CNS Drugs. 2011 PMID: 21936588
• Tsai Glycine transporter I inhibitor, N-methylglycine (Sarcosine), added to antipsychotics for the treatment of schizophrenia. Biol.Psychiatry 2004 PMID: 15023571

Product Documents for Sarcosine