Catalog Number: 2975
Chemical Name: N-Methylglycine
Biological Activity
Endogenous inhibitor of GlyT1 that displays antipsychotic activity. Potentiates the action of glycine on the NMDA glycine binding site.
Technical Data
  • M.Wt:
    89.09
  • Formula:
    C3H7NO2
  • Solubility:
    Soluble to 100 mM in water
  • Storage:
    Store at RT
  • CAS No:
    107-97-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Meta-analysis of the efficacy of adjunctive NMDA receptor modulators in chronic schizophrenia.
    Singh and Singh
    CNS Drugs., 2011;25:859
  2. Glycine transporter I inhibitor, N-methylglycine (Sarcosine), added to antipsychotics for the treatment of schizophrenia.
    Tsai et al.
    Biol.Psychiatry, 2004;55:452
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Sarcosine include:

1 Citations: Showing 1 - 1

  1. Glycine transporter type 2 (GlyT2) inhibitor ameliorates bladder overactivity and nociceptive behavior in rats.
    Authors: Yoshikawa Et al.
    Eur Urol 2012;62:704

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