Biological ActivitySarcosine is an endogenous inhibitor of GlyT1 that displays antipsychotic activity. Potentiates the action of glycine on the NMDA glycine binding site.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Meta-analysis of the efficacy of adjunctive NMDA receptor modulators in chronic schizophrenia.
Singh and Singh
CNS Drugs., 2011;25:859
Glycine transporter I inhibitor, N-methylglycine (Sarcosine), added to antipsychotics for the treatment of schizophrenia.
Tsai et al.
Citation for Sarcosine
The citations listed below are publications that use Tocris products. Selected citations for Sarcosine include:
1 Citation: Showing 1 - 1
Glycine transporter type 2 (GlyT2) inhibitor ameliorates bladder overactivity and nociceptive behavior in rats.
Authors: Yoshikawa Et al.
Eur Urol 2012;62:704
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