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Sauvagine

1609 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
1609/500U
Sauvagine
1 Image
Description: CRF agonist
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Biological Activity

Sauvagine is a corticotropin-releasing factor (CRF) receptor agonist. Ki values are 9.4, 9.9, and 3.8 nM for inhibition of 125I-[D-Tyr1]astressin binding to hCRF-R1, rCRF-R2a and mCRF-R2b respectively.

Technical Data

M.Wt:
4599.35
Formula:
C202H346N56O63S
Sequence:
XGPPISIDLSLELLRKMIEIEKQEKEKQQAANNRLLLDTI

(Modifications: X-1 = Glp, Ile-40 = C-terminal amide)

Storage:
Desiccate at -20°C
CAS No:
74434-59-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Actions of CRF and its analogues.
    Eckart et al.
    Curr.Med.Chem., 1999;6:1035
  2. Amino acid composition and sequence analysis of sauvagine, a new active peptide from the skin of PHYLLOMEDUSA SAWAGEI.
    Montecucchi and Henschen
    Int.J.Pept.Protein Res., 1981;18:113
  3. Corticotropin releasing factor receptors and their ligand family.
    Perrin and Vale
    Ann.N.Y.Acad.Sci., 1999;885:312

Product Datasheets

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