Biological ActivityCorticotropin-releasing factor (CRF) receptor agonist. Ki values are 9.4, 9.9, and 3.8 nM for inhibition of 125I-[D-Tyr1]astressin binding to hCRF-R1, rCRF-R2a and mCRF-R2b respectively.
(Modifications: X-1 = Glp, Ile-40 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Actions of CRF and its analogues.
Eckart et al.
Amino acid composition and sequence analysis of sauvagine, a new active peptide from the skin of PHYLLOMEDUSA SAWAGEI.
Montecucchi and Henschen
Int.J.Pept.Protein Res., 1981;18:113
Corticotropin releasing factor receptors and their ligand family.
Perrin and Vale
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