SB 205607 dihydrobromide

Key Product Details

Product Description

The first described non-peptide δ₁ opioid receptor agonist with very high affinity and selectivity for the δ₁ subtype (K_i values are 1.12, 2320 and 1790 nM at δ₁, μ and κ receptors respectively).

Licensing Information

Sold under license

Product Specifications for SB 205607 dihydrobromide

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for SB 205607 dihydrobromide

The following data is based on the product molecular weight 506.28.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

5 4 3 2 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.98 mL	9.88 mL	19.75 mL
5 mM	0.40 mL	1.98 mL	3.95 mL
10 mM	0.20 mL	0.99 mL	1.98 mL
50 mM	0.04 mL	0.20 mL	0.40 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

• Nagase Syntheses of non-peptidic delta opioid agonists and their structure-activity relationships. Jpn.J.Pharmacol.
• Knap Properties of TAN-67, a non-peptidic β-opioid receptor agonist, at cloned human δ- and μ-opioid receptors. Eur.J.Pharmacol. 1995 PMID: 8566162
• Nagase The pharmacological profile of δ opioid receptor ligands (+) and (-) TAN-67 on pain modulation. Life Sci. 2001 PMID: 11358331
• Kamei Antinociceptive effects of the selective non-peptidic δ-opioid receptor agonist TAN-67 in diabetic mice. Eur.J.Pharmacol. 1995 PMID: 7781682

Product Documents for SB 205607 dihydrobromide