SB 277011A dihydrochloride

Catalog # Availability Size / Price Qty
4207/10
4207/50
Dopamine D3 Receptor Antagonists Small Molecule
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Description: Selective D3 antagonist

Chemical Name: N-[trans-4-[2-(6-Cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]-4-quinolinecarboxamide dihydrochloride

Purity: ≥98%

Product Details
Citations (1)
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Biological Activity

Selective dopamine D3 receptor antagonist (pKi values are 8.0, 6.0, 5.0 and <5.2 for D3, D2, 5-HT1D and 5-HT1B respectively). Brain penetrant.

Technical Data

M.Wt:
511.49
Formula:
C28H30N4O.2HCl
Solubility:
Soluble to 5 mM in water and to 50 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at +4°C
CAS No:
1226917-67-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from GlaxoSmithKline.

Product Datasheets

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Citation for SB 277011A dihydrochloride

The citations listed below are publications that use Tocris products. Selected citations for SB 277011A dihydrochloride include:

1 Citation: Showing 1 - 1

  1. Electroacupuncture reduces cocaine-induced seizures and mortality in mice.
    Authors: Chen Et al.
    Nat Neurosci  2013;2013:134610

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