SB 277011A dihydrochloride

Catalog # Availability Size / Price Qty
SB 277011A dihydrochloride | CAS No. 1226917-67-4 | Dopamine D3 Receptor Antagonists
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Description: Selective D3 antagonist

Chemical Name: N-[trans-4-[2-(6-Cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]-4-quinolinecarboxamide dihydrochloride

Purity: ≥98%

Product Details
Citations (1)
Supplemental Products

Biological Activity

SB 277011A dihydrochloride is a selective dopamine D3 receptor antagonist (pKi values are 8.0, 6.0, 5.0 and <5.2 for D3, D2, 5-HT1D and 5-HT1B respectively). Brain penetrant.

Technical Data

Soluble to 50 mM in DMSO
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from GlaxoSmithKline.

Product Datasheets

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Citation for SB 277011A dihydrochloride

The citations listed below are publications that use Tocris products. Selected citations for SB 277011A dihydrochloride include:

1 Citation: Showing 1 - 1

  1. Electroacupuncture reduces cocaine-induced seizures and mortality in mice.
    Authors: Chen Et al.
    Nat Neurosci  2013;2013:134610


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