SB 408124

  ( 1 citations )    
Product Datasheet
Catalog Number:1963
Chemical Name:N-(6,8-Difluoro-2-methyl-4-quinolinyl)-N'-[4-(dimethylamino)phenyl]urea
Product Details
Citations (1)
Supplemental Products
Reviews
Biological Activity
Selective non-peptide orexin OX1 receptor antagonist (Kb values are 21.7 and 1405 nM for human OX1 and OX2 receptors respectively). Blocks orexin-A induced grooming following oral administration in vivo.
Technical Data
  • M.Wt:
    356.37
  • Formula:
    C19H18F2N4O
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    288150-92-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold for research purposes under agreement from GlaxoSmithKline
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for SB 408124 include:

1 Citations: Showing 1 - 1

  1. Orexins/hypocretins acting at Gi protein-coupled OX 2 receptors inhibit cyclic AMP synthesis in the primary neuronal cultures.
    Authors: Urbałska Et al.
    BMC Cancer  2012;46:42561

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