Home / BMP and Other Activin Receptor Activators / SB 4

SB 4

6881 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6881/50
SB 4 | CAS No. 100874-08-6 | BMP and Other Activin Receptor Activators
1 Image
Description: Potent BMP4 agonist

Chemical Name: 2-[[(4-Bromophenyl)methyl]thio]benzoxazole

Purity: ≥99%

Product Details
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

SB 4 is a potent BMP4 agonist (EC50 = 74 nM). Activates canonical BMP signaling and increases SMAD-1/5/9 phosphorylation, with no effect on p-SMAD-2, p-SMAD-3 or p-TAK1. Bypasses noggin-induced inhibition of type I BMP receptors.

Technical Data

M.Wt:
320.2
Formula:
C14H10BrNOS
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥99%
Storage:
Store at -20°C
CAS No:
100874-08-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for SB 4

There are currently no reviews for this product. Be the first to review SB 4 and earn rewards!

Have you used SB 4?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.