SB 4

Catalog # Availability Size / Price Qty
6881/50
SB 4 | CAS No. 100874-08-6 | BMP and Other Activin Receptor Activators
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Description: Potent BMP4 agonist

Chemical Name: 2-[[(4-Bromophenyl)methyl]thio]benzoxazole

Purity: ≥99%

Product Details
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Biological Activity

Potent BMP4 agonist (EC50 = 74 nM). Activates canonical BMP signaling and increases SMAD-1/5/9 phosphorylation, with no effect on p-SMAD-2, p-SMAD-3 or p-TAK1. Bypasses noggin-induced inhibition of type I BMP receptors.

Technical Data

M.Wt:
320.2
Formula:
C14H10BrNOS
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥99%
Storage:
Store at -20°C
CAS No:
100874-08-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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