SCH 221510

Catalog # Availability Size / Price Qty
3240/10
3240/50
SCH 221510 | CAS No. 322473-89-2 | NOP Receptor Agonists
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Description: Potent and selective NOP agonist

Chemical Name: 3-Endo-8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol

Purity: ≥99%

Product Details
Citations (1)
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Biological Activity

Potent and selective nociceptin opioid receptor (NOP) agonist (EC50 values are 12, 693, 683 and 8071 nM, and Ki values are 0.3, 65, 131 and 2854 nM at NOP, μ-, κ- and δ-opioid receptors respectively). Exhibits anxiolytic-like activity at doses that have no effect on overt behaviors such as locomotion in vivo. Orally active.

Technical Data

M.Wt:
397.55
Formula:
C28H31NO
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
322473-89-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for SCH 221510

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