Scopolamine hydrobromide

Catalog # Availability Size / Price Qty
Scopolamine hydrobromide | CAS No. 114-49-8 | Non-selective mAChR Antagonists
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Description: Non-selective muscarinic antagonist

Chemical Name: (α,S)-α-(Hydroxymethyl)benzeneacetic acid (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[,4]non-7-yl ester hydrobromide

Purity: ≥99%

Product Details
Citations (17)
Supplemental Products

Biological Activity

Scopolamine hydrobromide is a non-selective muscarinic antagonist. Widely used clinically to treat motion sickness.

Technical Data

Soluble to 100 mM in water and to 50 mM in DMSO
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Scopolamine hydrobromide

The citations listed below are publications that use Tocris products. Selected citations for Scopolamine hydrobromide include:

17 Citations: Showing 1 - 10

  1. Astroglia in lateral habenula is essential for antidepressant efficacy of light.
    Authors: Delcourte Et al.
    BioRXiv - not yet peer reviewed  2020;
  2. Cognitive enhancer effects of low Mem. doses are facilitated by an alpha7 nicotinic acetylcholine receptor agonist in scopolamine-induced amnesia in rats.
    Authors: Bali Et al.
    Front Pharmacol  2019;10:73
  3. DA Cells Differentially Regulate Striatal Cholinergic Transmission across Regions through Corelease of DA and Glutamate.
    Authors: Cai & Ford
    Cell Rep  2018;25:3148
  4. (2R,6R)-hydroxynorKA rescues chronic stress-induced depression-like behavior through its actions in the midbrain periaqueductal gray.
    Authors: Chou Et al.
    Neuropharmacology  2018;139:1
  5. The brain is required for normal muscle and nerve patterning during early Xenopus development.
    Authors: Herrera-Rincon Et al.
    Nat Commun  2017;8:587
  6. Impact of Altered Cholinergic Tones on the Neurovascular Coupling Response to Whisker Stimulation.
    Authors: Lecrux Et al.
    J Neurosci  2017;37:1518
  7. Nicotinic and opioid receptor regulation of striatal DA D2-receptor mediated transmission
    Authors: Mamaligas Et al.
    Scientific Reports  2016;6:37834
  8. σ1 receptor ligands control a switch between passive and active threat responses.
    Authors: Rennekamp Et al.
    Nat Chem Biol  2016;12:552
  9. Cholinergic and ghrelinergic receptors and KCNQ channels in the medial PFC regulate the expression of palatability.
    Authors: Parent Et al.
    Proc Natl Acad Sci U S A  2015;9:284
  10. Corelease of acetylcholine and GABA from cholinergic forebrain neurons.
    Authors: Saunders Et al.
    Front Behav Neurosci  2015;4


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