SD 1008

Tocris Bioscience | Catalog # 3035

JAK2/STAT3 signaling pathway inhibitor
Tocris Bioscience

Key Product Details

Description

JAK2/STAT3 signaling pathway inhibitor
View all STAT Inhibitors »

Product Description

SD 1008 is a JAK2/STAT3 signaling pathway inhibitor. Inhibits activation of STAT3, JAK2 and Src. Induces apoptosis in cell lines expressing constitutively active tyrosine-phosphorylated STAT3.

Product Specifications for SD 1008

Molecular Weight

329.35

Formula

C18H19NO5

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(1R,5R,6R,7S)-rel-4-Oxo-8-(phenylmethyl)-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid 6,7-dimethyl ester

CAS Number

960201-81-4

PubChem ID

90488795

InChI Key

XJLVVXLRQMISCS-ROINDZCWSA-N

SMILES

O=C1C=C[C@@H]2[C@@H]([C@](OC)=O)[C@@H]([C@](OC)=O)[C@H]1N2CC3=CC=CC=C3.O=C4C=C[C@H]5[C@H](C(OC)=O)[C@H](C(OC)=O)[C@@H]4N5CC6=CC=CC=C6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 32.94 100
Ethanol 1.65 5

Preparing Stock Solutions for SD 1008

The following data is based on the product molecular weight 329.35.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.04 mL 15.18 mL 30.36 mL
5 mM 0.61 mL 3.04 mL 6.07 mL
10 mM 0.30 mL 1.52 mL 3.04 mL
50 mM 0.06 mL 0.30 mL 0.61 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 8 publications citing the usage of this product.

Product Documents for SD 1008

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SD 1008

For research use only

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