Catalog Number: 2037
Chemical Name: 4-Amino-5-chloro-2-methoxybenzoic acid 2-(diethylamino)ethyl ester hydrochloride
Biological Activity
5-HT3/5-HT4 receptor antagonist.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
  • Storage:
    Desiccate at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. The action of SDZ 205,557 at 5-hydroxytryptamine (5-HT3 and 5-HT4) receptors.
    Eglen et al.
    Br.J.Pharmacol., 1993;108:376
  2. Antagonism of 5-hydroxytryptamine(4) receptors attenuates hyperactivity induced by cocaine: putative role for 5-hydroxytryptamine(4) receptors in the nucleus accumbens shell.
    McMahon and Cunningham
    J.Pharmacol.Exp.Ther., 1999;291:300
  3. SDZ 205-557, a selective, surmountable antagonist for 5-HT4 receptors in the isolated guinea pig ileum.
    Buchheit et al.
    Naunyn-Schmied.Arch.Pharmacol., 1992;345:387
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