receptor antagonist with low affinity for 5-HT1A
receptors. Inhibits [3
H]-mesulergine binding to 5-HT2C
receptors with a pKD
of 7.8. Inhibits 5-HT2B
mediated responses in the rat fundus (pKB
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Cataleptogenic effect of subtype selective 5-HT receptor antagonists in the rat.
Kalkman et al.
Role of 5-HT2A and 5-HT2C receptor subtypes in the two types of fear generated by the elevated T-maze.
Mora et al.
(+)-cis 4,5,7a,8,9,10,11,11a-Octahydro-7H-10-methylindolo[1,7-bc][2,6]-naphthyridine: a 5-HT2C/2B receptor antagonist with low 5-HT2A receptor affinity.
Nozulak et al.