SecinH3

Catalog # Availability Size / Price Qty
2849/10
2849/50
Cat.No. 2849 - SecinH3 | C24H20N4O4S | CAS No. 853625-60-2
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Description: Sec7-specific GEF inhibitor (cytohesins)

Chemical Name: N-[4-[5-(1,3-Benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)acetamide

Purity: ≥98%

Product Details
Citations (1)
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Biological Activity

Sec7-specific GEF inhibitor that displays selectivity for small GEFs of the cytohesin family (IC50 values are 2.4, 5.4, 5.4, 5.6, 5.6, 65 and > 100 μM for hCyh2, hCyh1, mCyh3, hCyh3, drosophila steppke, yGea2-S7 and hEFA6-S7 respectively). Inhibits insulin signaling via inhibition of insulin receptor substrate protein (IRS) phosphorylation.

Technical Data

M.Wt:
460.5
Formula:
C24H20N4O4S
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol with gentle warming
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
853625-60-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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Citation for SecinH3

The citations listed below are publications that use Tocris products. Selected citations for SecinH3 include:

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