Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry

Label

Biotin

Antibody Source

Monoclonal Mouse IgG1 Clone # 914419
View all Semaphorin 5A Primary Antibodies »

Product Specifications

Immunogen

NS0 mouse myeloma cell line transfected with human Semaphorin 5A
Glu23-Thr765
Accession # Q13591

Specificity

Detects human Semaphorin 5A in direct ELISAs.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Semaphorin 5A Antibody (914419) [Biotin]

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Semaphorin 5A

Members of the semaphorin protein family are involved in axonal guidance during neural development. Semaphorin 5a is thought to have a bifunctional role in axon guidance, exerting both attractive and inhibitory effects on developing axons associated with limbic function. The thrombospondin repeats of Semaphorin 5a physically interact with both heparan sulfate proteoglycans and chondroitin sulfate proteoglycans, inducing attractive and inhibitory guidance cues, respectively. The biological responses to Semaphorin 5a are induced through binding to its high-affinity receptor, plexin B3, triggering intracellular signaling through Met.

Alternate Names

SEMA5A, Semaphorin-F

Gene Symbol

SEMA5A

Additional Semaphorin 5A Products

Product Documents for Semaphorin 5A Antibody (914419) [Biotin]

Certificate of Analysis

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Product Specific Notices for Semaphorin 5A Antibody (914419) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Proteoglycans

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Protocols

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FAQs

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